Why dengue is deadlier the second time

“When the fever first struck, I might perhaps presumably no longer even instruct words,” acknowledged Tahmid Bashar Mahin, a 27-300 and sixty five days-extinct combating dengue for the first time.

For him, the diagnosis came after three days of unrelenting fever.

“I’m no longer experiencing any explicit challenges regarding my therapy. To instruct the least, the worth of getting the platelets test is Tk250, which has to be done most regularly so the worth will most seemingly be too great for sufferers from humble families,” he acknowledged.

The fresh dengue outbreak in Bangladesh has reached unheard of stages, with a loss of life toll of 488 this 300 and sixty five days as of 30 November, with six more deaths the earlier day, and three more on the present time. With day to day, the loss of life toll is nearing a legend 500 deaths in 2024.

Last 300 and sixty five days, 1,705 folk misplaced their lives attributable to dengue, making it the deadliest 300 and sixty five days on legend.

Over 3,000 sufferers are receiving therapy in hospitals all around the nation.

Since 1 January, a entire of 91,469 dengue cases had been reported.

Repeat infections are specifically harmful, as they vastly lift the threat of severe concerns delight in hemorrhagic fever, big internal bleeding, and liver damage.

Thought to be one of basically the most significant challenges lies in delayed therapy. Many sufferers before everything deal with indicators at home, easiest attempting to procure successfully being middle care when their condition worsens. This, coupled with an overstressed healthcare draw, has ended in sufferers being referred from one successfully being middle to one other, extra exacerbating the disaster.

The emotional toll of dengue is broad. In Dhaka, where the massive majority of cases are concentrated, families of victims are grappling with unexpected losses.

Amongst the fresh fatalities, many had been young adults, frail 16 to 35, who succumbed to concerns from reinfections.

Tahmid furthermore noted some precautions to preserve up a long way from getting infected the 2nd time. “I have change into more attentive to my ambiance. I strive and preserve up a long way from places with mosquitos in the morning and the afternoon.

“I have conception about applying mosquito repellent cream but don’t have any longer done so but but I’m searching out for to be in the mosquito gain as soon as I sleep.”

That’s the reason the 2nd time is great riskier

Dr Eshita Bishas, assistant professor on the Nationwide Scientific College,

explains, “Dengue can happen in four variants: DENV-1, DENV-2, DENV-3, and DENV-4. This means a person will most seemingly be infected up to four cases of their lifetime. Nonetheless, examine reveals that concerns are increased all the contrivance by contrivance of the 2nd infection attributable to a execrable-response between antibodies.”

When any person contracts dengue for the first time, the body develops antibodies to fight the virus. Nonetheless, all the contrivance by contrivance of a 2nd infection, these antibodies can problem off a severe immune response, main to concerns equivalent to Dengue Shock Syndrome (DSS) or internal bleeding. This immune response makes a 2nd infection deadlier and requires instantaneous medical attention.

Differentiating between first-time and subsequent dengue infections is no longer if truth be told continuously easy as many of us assemble no longer even glimpse or battle by contrivance of therapy after they are first infected with dengue.

“Clinically, the indicators might perhaps presumably appear the same,” Dr Bishas noted, including that categorical antibody assessments—measuring IgM and IgG stages can relief title the infection stage.

This diagnostic distinction is mandatory for the reason that 2nd infection’s severity most regularly is dependent on how early it is detected and treated.

For Mahbubur Rahman, a 28-300 and sixty five days-extinct who persevered dengue three cases, the 2nd infection became basically the most harrowing.

“My platelet depend dropped to 19,000 all the contrivance by contrivance of the 2nd time, main to blood clots and gum bleeding,” he shared.

By the third time, while his platelet depend became increased, he faced continual digestion factors that persist to this present day.

No topic taking precautions—delight in the use of mosquito nets and avoiding mosquito-vulnerable areas—Mahbub believes his living ambiance, a crowded university hall, contributed to his repeated infections.

“There is no longer any vaccine or medication to prevent it, and the necessities here [University hall] are finest for Aedes mosquitoes to thrive,” he lamented.

The fresh spike in dengue fatalities in Bangladesh brings out the importance of early intervention.

According to Dr Bishas, “Most deaths happen attributable to negligence or delayed medical attention.”

The World Effectively being Organization (WHO) recommends the TAK-003 vaccine for these travelling to dengue-endemic areas.

While this vaccine is no longer but commercially available in the market in Bangladesh, elevating consciousness about prevention and timely therapy stays severe.

In Dr Bishas’s journey of going by contrivance of dengue for the closing 24 years, she urged the authorities desirous to return to a permanent contrivance to this prolonged-standing successfully being disaster.

A be-cautious name for all

Mahin, now more cautious, avoids mosquito-vulnerable areas all the contrivance by contrivance of top cases and makes use of mosquito nets religiously. But, the concern of a doable 2nd infection lingers.

For Mahbub, every infection left lasting scars—physical and psychological.

“The doctors told me I’m a high-threat patient now. The relaxation can happen.”

Their reviews, alongside endless others, careworn the urgency of tackling dengue at its roots – bettering environmental prerequisites, investing in healthcare, and making vaccines accessible.

As Bangladesh grapples with this outbreak, the lesson is apparent that dengue is no longer a one-time fight. For more than just a few, the 2nd time might be the toughest—and continuously, the closing.